The 340B Drug Pricing Program is a US Department of Health and Human Services Health Resources and Services Administration (HRSA) program that requires participating drug wholesalers to sell drugs at a decreased cost to qualified entities on eligible prescriptions. It is administered by OPA, the Office of Pharmacy Affairs. The benefits of 340B are intended to help hospitals and other covered entities reach more eligible patients and provide more comprehensive services, improving their communities. Eligible hospitals may save an average of 25% to 50% on drug purchases for outpatient pharmacy distribution on prescriptions meeting the program criteria. At ACI, we stay informed about the 340B Drug Pricing Program and track legislative and regulatory changes to ensure that our clients are fully informed.